PRODUCT · HEMODYNAMIC MANAGEMENT

E-Fusion™

Adaptive vasopressor control, from decision support to full autonomy.

Schematic of the E-Fusion interface: infusion control, MAP gauge, target MAP, and total infused volume

E-Fusion is in development and has not been evaluated in human clinical studies. It is not available for sale or clinical use.

THE PROBLEM

Hemodynamic instability develops in seconds.

In sepsis, major trauma, and high-risk surgery, titrating vasopressors demands constant bedside vigilance, and even small delays matter.

THE REALITY
Blood pressure shifts rapidly
THE DEMAND
Constant manual titration
THE COST
Delays affect organ function
THE SOLUTION

Sense. Adapt. Titrate. Continuously.

E-Fusion pairs physiological modeling with adaptive control to track a patient's evolving condition and adjust therapy in real time, spanning a range from decision support to full closed-loop autonomy.

PEER-REVIEWED RESEARCH
A pilot study evaluating adaptive closed-loop fluid resuscitation during states of absolute and relative hypovolemia in dogs
Gholami B, Haddad WM, Bailey JM, Geist B, Ueyama Y, Muir WW (2018)
Journal of Veterinary Emergency and Critical Care
Closed-loop control for fluid resuscitation: Recent advances and future challenges
Gholami B, Haddad WM, Bailey JM, Muir WW (2021)
Frontiers in Veterinary Science